BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:Bioinformatics Seminar
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260716T164435Z
UID:tag:localist.com\,2008:EventInstance_50603361217566
DTSTART:20251001T153000Z
DTEND:20251001T170000Z
DESCRIPTION:Speaker: Benedict Paten (UC Santa Cruz)\n\nTitle: Furthering ou
 r understanding of human genetic variation: the human pangenome reference 
 project second release\n\nAbstract: Human genomics has relied on a single 
 reference genome for the last twenty years. This reference genome is a cor
 ner stone of much of what we do in genomics but it can not\, by definition
 \, represent the variation present in the human population\, and as a refe
 rence introduces a pervasive bias into genomic analyses. I will survey our
  recent efforts\, through the Human Pangenome Reference Consortium\, to bu
 ild and use a reference pangenome – a collection of extremely high-quali
 ty reference genomes related together by a consensus genome alignment that
  we intend as a replacement for the reference genome.\n\nBiography: Dr. Be
 nedict Paten is a professor in the department of Biomolecular Engineering 
 at the University of California\, Santa Cruz. He is also associate directo
 r of the UC Santa Cruz Genomics Institute. He received his Ph.D. in comput
 ational biology from the University of Cambridge and the European Molecula
 r Biology Laboratory. Dr. Paten’s work is broadly focused on the growing
  field of computational genomics. He is involved in a number of large-scal
 e efforts\, currently he is a PI of the Human Cell Atlas Data Platform\, t
 he NHGRI AnVIL\, HuBMAP\, GENCODE\, and the Human Pangenome Reference Cons
 ortium. Through these efforts he is helping to develop methods to further 
 our ability to assay and understand genomes.\n\nIn person or on Zoom at ht
 tps://mit.zoom.us/j/93513735220
GEO:42.361965;-71.090261
LOCATION:Building 32\, G575
SUMMARY:Bioinformatics Seminar
URL;VALUE=URI:https://calendar.mit.edu/event/bioinformatics-seminar-4418
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