Speaker:  Barbara Engelhardt (Stanford University)

Title:  Building 3D single-cell atlases

Abstract:  Comprehensive atlases of tissues, organs, and diseased tissues are being created regularly, but the definition of an 'atlas' remains unclear, and, as a result, the quality and consistency of available single cell atlases is variable. In this talk, I propose a definition for an atlas, and show models and methods we have developed to design, create, and annotate these atlases with minimal expert interventions. I show results benchmarking these methods on existing data and propose a series of future directions of study.

Bio: Barbara Engelhardt, PhD, is a Professor at Stanford University in the Department of Biomedical Data Studies and a Senior Investigator at Gladstone Institutes. Prior to taking these roles in 2022, she was a Professor at Princeton University in the Computer Science Department, and before that an Assistant Professor at Duke University. She earned her PhD at University of California, Berkeley, working with Prof. Michael I Jordan, and was a postdoc at the University of Chicago with Prof. Matthew Stephens. She has held positions in industry, including Google Research, 23andMe, and Genomics plc. She has won awards that include the Google Anita Borg Scholarship, the SMBE Walter M. Fitch Prize, a Sloan Faculty Fellowship, an NSF CAREER, and the ISCB Overton Prize. She is currently a CIFAR fellow in the Multiscale Human program.

In person or on Zoom at https://mit.zoom.us/j/93513735220