Hot Topics in Computing: Reversing Human Disease Circuitry

Thursday, March 17, 2022 at 4:00pm to 5:00pm

Star Seminar Room, Bldg. 32, 32-D463

Humanity is at a crossroads, where an aging population is confronting many new diseases, while genomics and machine learning advances are providing unprecedented opportunity for rewiring our cells to combat disease and aging. I will first describe recent advances in our lab for understanding the circuitry of Alzheimer's, obesity, heart disease, and psychiatric disorders at single cell resolution, and the steps we are taking for systematic manipulation of these circuits through high throughput experimentation and synthesis. I will then describe a vision for transforming clinical trials to enable precision medicine and personalized medicine, by focusing on the pathways and hallmarks underlying disease, and how they manifest at the genetic, epigenomic, transcriptional, and circuit level in each individual, and the resources that we need to put in place to enable this transformation across many sectors of science, technology, and finance. The goal of the evening is to use my comments for discussion, and to think how MIT, CSAIL, and our partners in hospitals, pharma, and biotechnology can work together to transform medicine and human health.

This is a hybrid event held on campus in the Star Seminar Room 32-D463, Stata Center/Bldg 32, 32 Vassar Street. Also available via Zoom (contact events AT csail DOT mit DOT edu for the Zoom channel information)

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Schwarzman College of Computing

Computer Science and Artificial Intelligence Laboratory (CSAIL)
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