This course is designed to introduce attendees to best practices in crystallographic structure determination with x-rays and electrons. Attendees will learn about XRD, electron diffraction, and scanning transmission electron microscopy on crystalline materials, with a primary focus on data analysis. A hands-on lab will be offered for XRD structure model refinement as well as an introduction to image analysis with the python package Atomap. Previous python experience is not required, but attendees will find introductory experience helpful. It is encouraged that attendees download anaconda before the course begins. This will be a 2-day course: one day for X-rays and one day for electrons.