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CALSCALE:GREGORIAN
X-WR-CALNAME:Nano Explorations: Implantable soft robotic platform for enhan
 ced drug delivery
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260719T162516Z
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DTSTART:20220308T160000Z
DTEND:20220308T164500Z
DESCRIPTION:An implantable soft robotic platform for enhanced drug delivery
 \n\nTuesday\, March 8\, 2022\n11 a.m. – 11:45 a.m. EST\n>>Register for t
 his Zoom webinar.\n\nDebkalpa Goswami\, Postdoctoral Associate\nInstitute 
 for Medical Engineering & Science (IMES)\n\nFibrous capsule formation\, an
 d its effect on molecular transport\, can be detrimental to the long-term 
 efficacy of implantable drug delivery devices\, especially when precise sp
 atial and temporal control is necessary for safe and effective therapy del
 ivery. In this talk\, Dr. Goswami will describe an implantable platform wh
 ich can overcome the diffusional barrier of the fibrous capsule to achieve
  enhanced transport of small and macromolecular therapy using multiple syn
 ergistic soft robotic strategies.\n\nUsing this platform\, small amplitude
  dynamic actuation (preconditioning) applied to subcutaneous tissue in mic
 e leads to a downstream functional effect: enhanced passive transport of i
 nsulin (a model macromolecule) and glycemic control. Furthermore\, rapid a
 ctuation of the platform at the time of drug delivery can accelerate trans
 port via convective fluid flow and overcome diffusional limitations caused
  by the fibrous capsule.\n\nThis soft actuatable platform has potential cl
 inical utility for mediating and overcoming the host fibrotic response\, l
 eading to enhanced delivery of drug therapy for a variety of indications\,
  such as diabetes.\n\n----------------------------------------------------
 ---\n\nNano Explorations is a virtual seminar series powered by MIT.nano t
 hat features presentations by MIT students and postdocs on their work in n
 anoscience\, nanotechnology\, and other advanced research fields.\n\nThe s
 eries was launched as a way to keep our nano community connected during th
 e COVID-19 pandemic. Presentations take place once a month and are open to
  any interested viewers.\n\nRead more about past and upcoming Nano Explora
 tions at mitnano.mit.edu/nano-explorations.
LOCATION:
SUMMARY:Nano Explorations: Implantable soft robotic platform for enhanced d
 rug delivery
URL;VALUE=URI:https://calendar.mit.edu/event/nano_explorations_implantable_
 soft_robotic_platform_for_enhanced_drug_delivery
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