Wednesday, March 20, 2024 | 4pm to 5pm
About this Event
43 VASSAR ST, Cambridge, MA 02139
https://scsb.mit.edu/event/scsb-colloquium-series-how-nature-and-nurture-conspire-to-regulate-brain-development-and-plasticity-michael-greenberg-ph-d/ #NeuroscienceDate: Wednesday, March 20, 2024
Location: 46-3002 (Singleton Auditorium) + Zoom Webinar: https://mit.zoom.us/j/99680612935
Speaker: Michael Greenberg, Ph.D.
Affiliation: Nathan Marsh Pusey Professor of Neurobiology, Harvard Medical School
Host: Dr. Elly Nedivi
Talk title: How Nature and Nurture Conspire to Regulate Brain Development and Plasticity
Abstract: Experience-dependent neuronal activity plays a critical role in shaping the connectivity and function of the central nervous system. These actions are mediated in part by the action of a program of neuronal activity-driven gene expression. Investigation of these gene expression programs has uncovered important roles in dendritic growth, the development of excitatory and inhibitory synapses, the composition of protein complexes at pre- and post-synaptic sites, and the production of neuropeptides that control neural circuit development. Moreover, defects in the activity-dependent gene program contribute to disorders of human cognition. Thus, study of this transcriptional response promises new insights into neuronal plasticity and disease.
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